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Trial Search

Current Search Criteria:

Intervention: Simeprevir 75 mg

Found 31 matching trials

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function

PHASE1

The purpose of this study is to evaluate the pharmacokinetics (PK) of AL-33...

Status

Withdrawn

Location

Multiple Locations

Start Date

2017-09-11

Trial ID

NCT03277755

Treatments Being Tested

AL-335 800 mg ODV 25 mg SMV 75 mg

TMC435-TiDP16-C125 - Study in Healthy Volunteers to Evaluate the Potential of TMC435 to Increase the Sensitivity of the Skin Towards Exposure to Sun Light

PHASE1

The purpose of the study is to evaluate the potential effect of TMC435 on t...

Status

Completed

Location

Multiple Locations

Start Date

2010-07

Trial ID

NCT01124799

Treatments Being Tested

TMC435 Placebo Ciprofloxacin

TMC435-TiDP16-C123 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents Efavirenz and Raltegravir

PHASE1

The purpose of this study is to investigate the effect of steady-state conc...

Status

Completed

Location

Multiple Locations

Start Date

2010-10

Trial ID

NCT01241773

Treatments Being Tested

raltegravir TMC435 + raltegravir TMC435 TMC435 + efavirenz TMC435 efavirenz

Sofosbuvir With Ribavirin or Simeprevir With HCV GT4 Egyptian Patients

PHASE2

A total of 201 participants with chronic HCV GT4 infection were allocated i...

Status

Completed

Location

Multiple Locations

Start Date

2015-04

Trial ID

NCT04385407

Treatments Being Tested

Sofosbuvir + Simeprevir + Ribavirin

Early Treatment of Recurrent HCV- Infection Post Liver Transplantation in the Era of DAAs

PHASE4

The study aimed to present our experience in treating recurrent HCV genotyp...

Status

Completed

Location

Multiple Locations

Start Date

2014-09

Trial ID

NCT03133065

Treatments Being Tested

treatment of HCV with oral direct acting antiviral therapy

A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus

PHASE2

The purpose of this study is to explore the efficacy and safety of TMC64705...

Status

Completed

Location

Multiple Locations

Start Date

2012-10

Trial ID

NCT01724086

Treatments Being Tested

TMC647055 TMC435 Ritonavir Ribavirin Pegylated interferon alpha-2a (PegIFN)GSK2336805

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TMC647055 in Combination With Ritonavir (Part 1) and the Co-administration of TMC435, TMC647055 and Ritonavir (Part 2) in Healthy Japanese Participants

PHASE1

The purpose of the study is to investigate the safety, tolerability, and ph...

Status

Completed

Location

Multiple Locations

Start Date

2014-02

Trial ID

NCT02064842

Treatments Being Tested

TMC647055 TMC435 Placebo Ritonavir (RTV)

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of the Combination of AL-335, Odalasvir, and Simeprevir

PHASE2

The purpose of this study is to evaluate the safety and tolerability of AL-...

Status

Completed

Location

CAP Research Ltd

Start Date

2015-10-31

Trial ID

NCT02569710

Treatments Being Tested

AL-335 Odalasvir (ODV)Simeprevir (SMV)

A Study of TMC435 in Combination With PSI-7977 (GS7977) in Chronic Hepatitis C Genotype 1-Infected Prior Null Responders To Peginterferon/Ribavirin Therapy or HCV Treatment-Naive Patients

PHASE2

The purpose of this study is to investigate the efficacy and safety of TMC4...

Status

Completed

Location

Multiple Locations

Start Date

2012-01

Trial ID

NCT01466790

Treatments Being Tested

TMC435 PSI-7977 (GS7977)Ribavirin

Samatasvir (IDX719) in Combinations With Simeprevir and/or TMC647055/Ritonavir With or Without Ribavirin for 12 Weeks in Participants With Chronic Hepatitis C Infection (MK-1894-005)

PHASE2

Parts A and B of this study are designed to evaluate the safety, tolerabili...

Status

Completed

Location

Multiple Locations

Start Date

2013-03

Trial ID

NCT01852604

Treatments Being Tested

Samatasvir Simeprevir Ribavirin (RBV)TMC647055 Ritonavir (RTV)Pegylated interferon (Peg-IFN)Samatasvir matching placebo

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